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How Cardiologists’ High Hopes for Two Drugs Were Dashed
By every measure, the drugs were no better than placebos, full data revealed on Saturday. Was it the fault of the design of the studies, or our very hypotheses about heart disease?
STAT+: Failure of Novartis Lp(a) drug raises questions about cardiovascular strategy
Medical mystery at the AHA conference: A Novartis drug lowered a risk marker for cardiovascular disease but did not lower chance of heart attack or stroke.
A promising new medicine against heart disease fails unexpectedly
Doctors expected an experimental drug that lowers a common risk factor for heart attacks would save patients' lives. The medicine made no difference.
The ‘slam dunk’ that wasn’t: Promising cholesterol drug fails to prevent heart attacks or stroke
An experimental drug that held great promise in driving down a dangerous form of cholesterol didn’t show any measurable impact on heart attack or stroke in a clinical trial.
STAT+: Despite Novo drug’s failure, cardiologists say they will still pursue anti-inflammatories
“These results, the fact that they're negative, does not invalidate that inflammation plays a very important role in cardiovascular disease."
The introduction of a medieval public health system exposed the population to roundworm
Medieval health and sanitation efforts involved deliberate interventions; however, some of these measures had the opposite effect, leading to an increased spread of disease in Trondheim.
Islamist Militant Attack Forces Patients to Flee Ebola Clinic in Congo
At least 44 people were killed in a brutal assault by a group loyal to the Islamic State, officials said. The area is a hot spot of the growing Ebola outbreak.
This teen boy set out to get people talking about periods. He's now a Diana honoree
This year's the Princess Diana honor roll highlights 198 inspiring young activists and advocates — including an 18-year-old guy in India who founded Team Period.
Drinking 2–3 cups of coffee a day linked to dramatically lower dementia risk
Drinking two to three cups of caffeinated coffee daily was linked to a dramatically lower risk of dementia and better cognitive functioning in a study spanning up to 43 years. The benefits appeared regardless of genetic risk, but decaffeinated coffee did not show the same association.
CDC reports more than 5,000 measles cases, highest number in 35 years
Children and teenagers make up almost 60 percent of confirmed cases.
Pope Leo XIV arrives for South American tour after cancer surgery
Pope Leo XIV arrives in Uruguay kicking off a 12-day tour of South America after undergoing lung surgery last month.
U.S. on verge of losing measles elimination status as number of cases grows
The United States is on the verge of losing its measles elimination status as cases top 5,000 nationwide for the first time in more than three decades. Pennsylvania, New York and Wisconsin have all reported measles-related deaths this week.
A compound hidden in broccoli could help fight a devastating genetic disease
A compound naturally found in broccoli could help fight Friedreich ataxia, a devastating genetic disease that progressively damages the nervous system, by boosting a vital protein and protecting nerve cells. Scientists hope the discovery could lead to an affordable treatment, although clinical trials are still needed to establish its effectiveness in patients.
Man unexpectedly recovers from a knife wound through his eye and brain
It's the exact path, not the apparent severity that matters most, doctors say.
STAT+: States sue Trump administration again to delay Medicaid work requirements
The Trump administration is facing another lawsuit over its sweeping changes to Medicaid less than a week after a federal judge ruled that implementation of work requirements would cause “irreparable…
Biotech Firm Claims Some Credit for Groundbreaking Virus Research
Radical Numerics turned heads with its announcement about a novel treatment. Now a former partner, Tabula Bioscience, says it performed much of the research.
Two incoming lawmakers plan to defend health equity from Trump administration cuts
Two newly elected lawmakers with science backgrounds hope to push back against Trump administration cuts to health equity programs.
Pope voted in U.S. election because he's "proud to be an American"
Pope Leo, who is on a 12-day, three-country trip in Latin America, also said he credits God and doctors for his lung cancer surgery recovery.
Light-powered method resurrects 'dead-end' compounds for drug discovery
Throughout the drug development process, which can take a decade or more, tens of thousands of chemical compounds are produced that never go on to become medicines. A Florida State University researcher is part of a team that has discovered a new way to give some of these "dead ends" a second chance at becoming the foundation for tomorrow's blockbuster drugs.
Sen. Chris Murphy out of hospital, will miss votes after stroke
Murphy's doctor said he expects the senator to "make a full recovery following rehabilitation."